Padecimientos y estudios
Guía de padecimientos y estudios
Infórmate
La distribución del Sistema Endocannabinoide en el organismo humano, está conforma por receptores y moléculas llamadas endocannabinoides. Razón por la cual el cannabis puede ser utilizado como medicamento y tratar una amplia gama de padecimientos que atacan los siguientes sistemas y aparatos del cuerpo:
- Inmunológico
- Nervioso
- Cardiovascular
- Gastrointestinal
- Respiratorio
- Reproductor, e incluso el óseo.
A continuación encontrarás un compilado de artículos de relevancia médica al respecto del uso de cannabinoides en diversas enfermedades en las que la ciencia ha sugerido su efectividad. Cabe mencionar que la gran mayoría de los artículos aquí referidos son de protocolos de estudios preclínicos, de investigación en animales y con cultivos celulares desarrollados en laboratorios.
Lo anterior, debido a las legislaciones prohibicionistas de algunos países, ya que al ser muy pocos los gobiernos que permiten realizar estudios en humanos, los que existen sólo se han hecho con productos farmacéuticos derivados de la planta del Cannabis.
Si bien es cierto que se encuentran estudios y artículos relacionados con los padecimientos y el uso de cannabis en México, todos de ellos son en fase pre clínica. Aunque en un futuro, es probable que México realice investigaciones clínicas para contribuir al desarrollo científico del cannabis medicinal.
In vivo evidence for therapeutic of canabidio cbd for alzheimer disease
Cannabinoids in late-onset Alzheimer’s disease.
CB2 receptor and amyloid pathology in frontal cortex of Alzheimer’s disease patients.
Endocannabinoid regulation of amyloid-induced neuroinflammation.
Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease.
Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic.
Endocannabinoid signalling in Alzheimer’s disease.
In vivo type 1 cannabinoid receptor availability in Alzheimer’s disease.
The therapeutic potential of the endocannabinoid system for Alzheimer’s disease.
Endocannabinoids prevent β-amyloid-mediated lysosomal destabilization in cultured neurons.
The Endocannabinoid System and Anxiety.
Evidences for the Anti-panic Actions of Cannabidiol.
Cannabidiol as a Potential Treatment for Anxiety Disorders.
Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.
Cannabidiol Regulation of Learned Fear: Implications for Treating Anxiety-Related Disorders.
Cannabidiol Oil for Decreasing Addictive Use of Marijuana: A Case Report.
General
Publicaciones del Grupo de Señalización por Cannabinoides dirigido por el Dr. Manuel Guzmán
Towards the use of cannabinoids as antitumour agents.
A selective review of medical cannabis in cancer pain management.
Cannabis Use in Palliative Oncology: A Review of the Evidence for Popular Indications.
Cannabinoids – a new weapon against cancer?
Cannabidiol as potential anticancer drug.
A user’s guide to cannabinoid therapies in oncology.
Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics.
Integrating cannabis into clinical cancer care.
Cannabidiol, a novel inverse agonist for GPR12.
Cannabidiol inhibits angiogenesis by multiple mechanisms.
Cannabis and cancer: toward a new understanding.
Systematic Review of the Use of Phytochemicals for Management of Pain in Cancer Therapy.
The influence of biomechanical properties and cannabinoids on tumor invasion.
Antitumorigenic targets of cannabinoids – current status and implications.
Cerebro
A combined preclinical therapy of cannabinoids and temozolomide against glioma.
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma.
Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells.
Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines.
De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis.
Pulmón
Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.
COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells.
Estomago
Colon
Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.
GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis.
Próstata
Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.
Seno
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer.
Páncreas
Urológico
Targeting the endogenous cannabinoid system to treat neuropathic pain.
The endocannabinoid system as a potential therapeutic target for pain modulation.
Endocannabinoid system: Role in depression, reward and pain control (Review).
Cannabinoids in the management of chronic pain: a front line clinical perspective.
A selective review of medical cannabis in cancer pain management.
Chronic pain patients’ perspectives of medical cannabis.
Opioids Out, Cannabis In Negotiating the Unknowns in Patient Care for Chronic Pain
Inhaled Cannabis for Chronic Neuropathic Pain: A Meta-analysis of Individual Patient Data.
Medical Marijuana and Chronic Pain: a Review of Basic Science and Clinical Evidence.
The role of the endocannabinoid system in pain.
Prescribing smoked cannabis for chronic noncancer pain: preliminary recommendations.
Dronabinol and chronic pain: importance of mechanistic considerations.
Cannabis as an adjunct to or substitute for opiates in the treatment of chronic pain.
Prescribing marijuana for chronic pain.
The analgesic potential of cannabinoids.
Endocannabinoid system acts as a regulator of immune homeostasis in the gut.
Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.
Irritable Bowel Syndrome: A Dysfunction of the Endocannabinoid System?
The Role of the Endocannabinoid System in the Brain-Gut Axis.
The gastrointestinal tract – a central organ of cannabinoid signaling in health and disease.
Role of cannabis in digestive disorders.
Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go?
Cannabis and Multiple Sclerosis—The Way Forward´
Cannabis and cognitive functioning in multiple sclerosis: The role of gender.
Symptomatic therapy in multiple sclerosis: the role of cannabinoids in treating spasticity
Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis.
Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis
Clinical perspectives on medical marijuana (cannabis) for neurologic disorders.
Advances in the management of MS spasticity: recent observational studies.
Advances in the management of multiple sclerosis spasticity: recent clinical trials.
Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters.